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Evaluation of Adverse Drug Properties with Cryopreserved Human Hepatocytes and the Integrated Discrete Multiple Organ Co-culture (IdMOC(TM)) System
Human hepatocytes, with complete hepatic metabolizing enzymes, transporters and cofactors, represent the gold standard for in vitro evaluation of drug metabolism, drug-drug interactions, and hepatotoxicity. Successful cryopreservation of human hepatocytes enables this experimental system to be used...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Korean Society Of Toxicology
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505344/ https://www.ncbi.nlm.nih.gov/pubmed/26191380 http://dx.doi.org/10.5487/TR.2015.31.2.137 |