Cargando…

Novel Role for γ-Catenin in the Regulation of Cancer Cell Migration via the Induction of Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1)

γ-catenin (Plakoglobin), a well-described structural protein functioning at the adherens junctions and desmosomes, was shown to be either lost or weakly expressed in non-small cell lung cancer (NSCLC) cells and tumor tissues. However, the tumor suppressive affects of γ-catenin were not fully underst...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sechler, Marybeth, Borowicz, Stanley, Van Scoyk, Michelle, Avasarala, Sreedevi, Zerayesus, Sereke, Edwards, Michael G., Kumar Karuppusamy Rathinam, Manoj, Zhao, Xiangmin, Wu, Pei-Ying, Tang, Ke, Bikkavilli, Rama Kamesh, Winn, Robert A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505473/ https://www.ncbi.nlm.nih.gov/pubmed/25925948 http://dx.doi.org/10.1074/jbc.M114.631820

Ejemplares similares

PRMT1 Is a Novel Regulator of Epithelial-Mesenchymal-Transition in Non-small Cell Lung Cancer
por: Avasarala, Sreedevi, et al.
Publicado: (2015)

Non-small-cell lung cancer: molecular targeted therapy and personalized medicine – drug resistance, mechanisms, and strategies
por: Sechler, Marybeth, et al.
Publicado: (2013)

K-homology splicing regulatory protein (KSRP) promotes post-transcriptional destabilization of Spry4 transcripts in non-small cell lung cancer
por: Bikkavilli, Rama Kamesh, et al.
Publicado: (2017)

Dishevelled3 is a novel arginine methyl transferase substrate
por: Bikkavilli, Rama Kamesh, et al.
Publicado: (2012)

hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression
por: Avasarala, Sreedevi, et al.
Publicado: (2013)

Heterotrimeric G-Protein, G(α16), Is a Critical Downstream Effector of Non-Canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer
por: Avasarala, Sreedevi, et al.
Publicado: (2013)

Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer
por: Bikkavilli, R K, et al.
Publicado: (2015)

Erratum: Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer
por: Bikkavilli, R K, et al.
Publicado: (2015)

Arginine methylation of G3BP1 in response to Wnt3a regulates β-catenin mRNA
por: Bikkavilli, Rama Kamesh, et al.
Publicado: (2011)

Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2
por: Bikkavilli, Rama Kamesh, et al.
Publicado: (2012)

HAI-1 is an independent predictor of lung cancer mortality and is required for M1 macrophage polarization
por: Borowicz, Stanley, et al.
Publicado: (2021)

Prognostic significance of hepatocyte growth factor activator inhibitor type 1 (HAI-1) immunoreactivity in pancreatic ductal adenocarcinoma
por: Sakugawa, Chihiro, et al.
Publicado: (2017)

Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation
por: Lai, Chih-Hsin, et al.
Publicado: (2016)

Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency–Associated Developmental Defects by Preventing Matriptase Activation
por: Szabo, Roman, et al.
Publicado: (2012)

Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin
por: Lee, Shiao-Pieng, et al.
Publicado: (2018)

Correction: Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin
por: Lee, Shiao-Pieng, et al.
Publicado: (2018)

Incidence of Healthcare-Associated Infections (HAIs) and the adherence to the HAIs’ prevention strategies in a military hospital in Alkharj
por: Ahmed, Nehad J., et al.
Publicado: (2021)

Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity
por: Chiu, Yi-Lin, et al.
Publicado: (2020)

Promoter Hypomethylation Is Responsible for Upregulated Expression of HAI-1 in Hepatocellular Carcinoma
por: Du, Xiaoxiao, et al.
Publicado: (2019)

Health Care–Associated Infections (HAIs)
por: Almeida, Sherri-Lynne
Publicado: (2015)

Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes
por: Wu, Heng, et al.
Publicado: (2023)

The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis
por: Sechler, Marybeth, et al.
Publicado: (2017)

Stromal Hyaluronan Interaction with Epithelial CD44 Variants Promotes Prostate Cancer Invasiveness by Augmenting Expression and Function of Hepatocyte Growth Factor and Androgen Receptor
por: Ghatak, Shibnath, et al.
Publicado: (2010)

Ár njöt'i ar hai = El color de la tierra
Publicado: (2014)

Hepatocyte growth factor activator inhibitor type-2 (HAI-2)/SPINT2 contributes to invasive growth of oral squamous cell carcinoma cells
por: Yamamoto, Koji, et al.
Publicado: (2018)

Gold Standard Evaluation of an Automatic HAIs Surveillance System
por: Villamarín-Bello, Beatriz, et al.
Publicado: (2019)

Understanding HAIs: Ally proteins in the fight against cancer
por: Nonboe, Annika W., et al.
Publicado: (2022)

KDM3A/Ets1/MCAM axis promotes growth and metastatic properties in Rhabdomyosarcoma
por: Sobral, Lays Martin, et al.
Publicado: (2020)

Endoscopic endonasal approach to the craniocervical junction: the importance of anterior C1 arch preservation or its reconstruction
por: Re, M., et al.
Publicado: (2016)

The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury
por: Chen, Zongyu, et al.
Publicado: (2023)

ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription
por: Riou, Rozenn, et al.
Publicado: (2020)

The concordance of European and US definitions for healthcare-associated infections (HAI)
por: Hansen, S, et al.
Publicado: (2011)

Social representation and practices related to dementia in Hai District of Tanzania
por: Mushi, Declare, et al.
Publicado: (2014)

Validation of the Human–Animal Interaction Scale (HAIS) in Czech Language
por: Machová, Kristýna, et al.
Publicado: (2020)

Ethics in the Time of Coronavirus: Engaging the Conversation: In Reply to Hai and Colleagues
por: Kramer, Jessica B., et al.
Publicado: (2020)

Epidemiology of Healthcare-Associated Infections and Adherence to the HAI Prevention Strategies
por: Alrebish, Saleh A., et al.
Publicado: (2022)

What risks to sustainability are identified throughout care bundle implementation and how can they be addressed? A mixed methods case study
por: Lennox, Laura, et al.
Publicado: (2021)

Gene signatures related to HAI response following influenza A/H1N1 vaccine in older individuals
por: Ovsyannikova, Inna G., et al.
Publicado: (2016)

Regulation of matriptase and HAI-1 system, a novel therapeutic target in human endometrial cancer cells
por: Sun, Pengming, et al.
Publicado: (2018)

Exploring the roles of urinary HAI-1, EpCAM & EGFR in bladder cancer prognosis & risk stratification
por: Snell, Kym I.E., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_0emj2edbvmvac42dh1jd21k93n