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Expanding Regulatory T Cells Alleviates Chikungunya Virus-Induced Pathology in Mice

Chikungunya virus (CHIKV) infection is a reemerging pandemic human arboviral disease. CD4(+) T cells were previously shown to contribute to joint inflammation in the course of CHIKV infection in mice. The JES6-1 anti-IL-2 antibody selectively expands mouse regulatory T cells (Tregs) by forming a com...

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Detalles Bibliográficos
Autores principales:	Lee, Wendy W. L., Teo, Teck-Hui, Her, Zhisheng, Lum, Fok-Moon, Kam, Yiu-Wing, Haase, Doreen, Rénia, Laurent, Rötzschke, Olaf, Ng, Lisa F. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2015
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505607/ https://www.ncbi.nlm.nih.gov/pubmed/25995249 http://dx.doi.org/10.1128/JVI.00998-15

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