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Conformational Changes in Two Inter-Helical Loops of Mhp1 Membrane Transporter
Mhp1 is a bacterial secondary transporter with high-resolution crystal structures available for both the outward- and inward-facing conformations. Through molecular dynamics simulations of the ligand-free Mhp1 as well as analysis of its crystal structures, here we show that two inter-helical loops,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505851/ https://www.ncbi.nlm.nih.gov/pubmed/26186341 http://dx.doi.org/10.1371/journal.pone.0133388 |