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Towards the Personalized Treatment of Glioblastoma: Integrating Patient-Specific Clinical Data in a Continuous Mechanical Model
Glioblastoma multiforme (GBM) is the most aggressive and malignant among brain tumors. In addition to uncontrolled proliferation and genetic instability, GBM is characterized by a diffuse infiltration, developing long protrusions that penetrate deeply along the fibers of the white matter. These feat...
Autores principales: | Colombo, Maria Cristina, Giverso, Chiara, Faggiano, Elena, Boffano, Carlo, Acerbi, Francesco, Ciarletta, Pasquale |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505854/ https://www.ncbi.nlm.nih.gov/pubmed/26186462 http://dx.doi.org/10.1371/journal.pone.0132887 |
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