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Augmented Endothelial-Specific L-Arginine Transport Blunts the Contribution of the Sympathetic Nervous System to Obesity Induced Hypertension in Mice

Augmenting endothelial specific transport of the nitric oxide precursor L-arginine via cationic amino acid transporter-1 (CAT1) can prevent obesity related hypertension. We tested the hypotheses that CAT1 overexpression prevents obesity-induced hypertension by buffering the influence of the sympathe...

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Detalles Bibliográficos
Autores principales: Rajapakse, Niwanthi W., Karim, Florian, Evans, Roger G., Kaye, David M., Head, Geoffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505872/
https://www.ncbi.nlm.nih.gov/pubmed/26186712
http://dx.doi.org/10.1371/journal.pone.0131424

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