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IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism
IL-10 is produced by macrophages in diverse immune settings and is critical in limiting immune-mediated pathology. In helminth infections, macrophages are an important source of IL-10; however, the molecular mechanism underpinning production of IL-10 by these cells is poorly characterized. In this s...
Autores principales: | Sanin, David E., Prendergast, Catriona T., Mountford, Adrian P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505959/ https://www.ncbi.nlm.nih.gov/pubmed/26116503 http://dx.doi.org/10.4049/jimmunol.1500146 |
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