Cargando…
Noninvasive Evaluation of Myocardial Systolic Dysfunction in the Early Stage of Kawasaki Disease: A Speckle-Tracking Echocardiography Study
BACKGROUND: Evaluation of myocardial function by speckle-tracking echocardiography is a new method for the early diagnosis of systolic dysfunction. OBJECTIVES: We aimed to determine myocardial speckle-tracking echocardiography indices in Kawasaki Disease (KD) patients and compare them with the same...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505983/ https://www.ncbi.nlm.nih.gov/pubmed/26199701 http://dx.doi.org/10.5812/ijp.25(3)2015.198 |
_version_ | 1782381618667716608 |
---|---|
author | Hematian, Mohammad-Nasir Torabi, Shirin MalaKan-Rad, Elaheh Sayadpour-Zanjani, Keyhan Ziaee, Vahid Lotfi-Tolkaldany, Masoumeh |
author_facet | Hematian, Mohammad-Nasir Torabi, Shirin MalaKan-Rad, Elaheh Sayadpour-Zanjani, Keyhan Ziaee, Vahid Lotfi-Tolkaldany, Masoumeh |
author_sort | Hematian, Mohammad-Nasir |
collection | PubMed |
description | BACKGROUND: Evaluation of myocardial function by speckle-tracking echocardiography is a new method for the early diagnosis of systolic dysfunction. OBJECTIVES: We aimed to determine myocardial speckle-tracking echocardiography indices in Kawasaki Disease (KD) patients and compare them with the same indices in control subjects. PATIENTS AND METHODS: Thirty-two patients (65.5% males) with KD and 19 control subjects with normal echocardiography participated in this study. After their demographic characteristics and clinical findings were recorded, all the participants underwent transthoracic echocardiography. Strain (S), Strain Rate (SR), Time to Peak Strain (TPS), and Strain Rate (TPSR), longitudinal velocity and view point velocity images in the two, three, and four-chamber views were semi-automatically obtained via speckle-tracking echocardiography. RESULTS: Among the patients, Twenty-four cases (75%) were younger than 4 years. Mean global S and SR was significantly reduced in the KD patients compared to controls (17.03 ± 1.28 vs. 20.22 ± 2.14% and 1.66 ± 0.16 vs. 1.97 ± 0.25 1/second, respectively), while there were no significant differences regarding mean TPS, TPSR, longitudinal velocity and view point velocity. Using repeated measure of analysis of variances, we observed that S and SR decreased from base to apical level in both groups. The change in the pattern of age adjusted mean S and SR across levels was significantly different between the groups (P < 0.001 for both parameters). CONCLUSIONS: We showed changes in S and SR assessed in KD patients versus control subjects in the acute phase of KD. However, we suggest that further studies be undertaken to compare S and SR in the acute phase and thereafter in KD patients. |
format | Online Article Text |
id | pubmed-4505983 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Kowsar |
record_format | MEDLINE/PubMed |
spelling | pubmed-45059832015-07-21 Noninvasive Evaluation of Myocardial Systolic Dysfunction in the Early Stage of Kawasaki Disease: A Speckle-Tracking Echocardiography Study Hematian, Mohammad-Nasir Torabi, Shirin MalaKan-Rad, Elaheh Sayadpour-Zanjani, Keyhan Ziaee, Vahid Lotfi-Tolkaldany, Masoumeh Iran J Pediatr Research Article BACKGROUND: Evaluation of myocardial function by speckle-tracking echocardiography is a new method for the early diagnosis of systolic dysfunction. OBJECTIVES: We aimed to determine myocardial speckle-tracking echocardiography indices in Kawasaki Disease (KD) patients and compare them with the same indices in control subjects. PATIENTS AND METHODS: Thirty-two patients (65.5% males) with KD and 19 control subjects with normal echocardiography participated in this study. After their demographic characteristics and clinical findings were recorded, all the participants underwent transthoracic echocardiography. Strain (S), Strain Rate (SR), Time to Peak Strain (TPS), and Strain Rate (TPSR), longitudinal velocity and view point velocity images in the two, three, and four-chamber views were semi-automatically obtained via speckle-tracking echocardiography. RESULTS: Among the patients, Twenty-four cases (75%) were younger than 4 years. Mean global S and SR was significantly reduced in the KD patients compared to controls (17.03 ± 1.28 vs. 20.22 ± 2.14% and 1.66 ± 0.16 vs. 1.97 ± 0.25 1/second, respectively), while there were no significant differences regarding mean TPS, TPSR, longitudinal velocity and view point velocity. Using repeated measure of analysis of variances, we observed that S and SR decreased from base to apical level in both groups. The change in the pattern of age adjusted mean S and SR across levels was significantly different between the groups (P < 0.001 for both parameters). CONCLUSIONS: We showed changes in S and SR assessed in KD patients versus control subjects in the acute phase of KD. However, we suggest that further studies be undertaken to compare S and SR in the acute phase and thereafter in KD patients. Kowsar 2015-06-27 2015-06 /pmc/articles/PMC4505983/ /pubmed/26199701 http://dx.doi.org/10.5812/ijp.25(3)2015.198 Text en Copyright © 2015, Growth & Development Research Center. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. |
spellingShingle | Research Article Hematian, Mohammad-Nasir Torabi, Shirin MalaKan-Rad, Elaheh Sayadpour-Zanjani, Keyhan Ziaee, Vahid Lotfi-Tolkaldany, Masoumeh Noninvasive Evaluation of Myocardial Systolic Dysfunction in the Early Stage of Kawasaki Disease: A Speckle-Tracking Echocardiography Study |
title | Noninvasive Evaluation of Myocardial Systolic Dysfunction in the Early Stage of Kawasaki Disease: A Speckle-Tracking Echocardiography Study |
title_full | Noninvasive Evaluation of Myocardial Systolic Dysfunction in the Early Stage of Kawasaki Disease: A Speckle-Tracking Echocardiography Study |
title_fullStr | Noninvasive Evaluation of Myocardial Systolic Dysfunction in the Early Stage of Kawasaki Disease: A Speckle-Tracking Echocardiography Study |
title_full_unstemmed | Noninvasive Evaluation of Myocardial Systolic Dysfunction in the Early Stage of Kawasaki Disease: A Speckle-Tracking Echocardiography Study |
title_short | Noninvasive Evaluation of Myocardial Systolic Dysfunction in the Early Stage of Kawasaki Disease: A Speckle-Tracking Echocardiography Study |
title_sort | noninvasive evaluation of myocardial systolic dysfunction in the early stage of kawasaki disease: a speckle-tracking echocardiography study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505983/ https://www.ncbi.nlm.nih.gov/pubmed/26199701 http://dx.doi.org/10.5812/ijp.25(3)2015.198 |
work_keys_str_mv | AT hematianmohammadnasir noninvasiveevaluationofmyocardialsystolicdysfunctionintheearlystageofkawasakidiseaseaspeckletrackingechocardiographystudy AT torabishirin noninvasiveevaluationofmyocardialsystolicdysfunctionintheearlystageofkawasakidiseaseaspeckletrackingechocardiographystudy AT malakanradelaheh noninvasiveevaluationofmyocardialsystolicdysfunctionintheearlystageofkawasakidiseaseaspeckletrackingechocardiographystudy AT sayadpourzanjanikeyhan noninvasiveevaluationofmyocardialsystolicdysfunctionintheearlystageofkawasakidiseaseaspeckletrackingechocardiographystudy AT ziaeevahid noninvasiveevaluationofmyocardialsystolicdysfunctionintheearlystageofkawasakidiseaseaspeckletrackingechocardiographystudy AT lotfitolkaldanymasoumeh noninvasiveevaluationofmyocardialsystolicdysfunctionintheearlystageofkawasakidiseaseaspeckletrackingechocardiographystudy |