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Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study

BACKGROUND: Thalassemia is an inherited blood disease. It is a serious public health problem throughout the Mediterranean region, the Middle East and the Indian subcontinent, as well as in Southeast Asia. OBJECTIVES: Thalassemia is an inherited blood disease. It is a serious public health problem. I...

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Autores principales: Behdani, Fatemeh, Badiee, Zahra, Hebrani, Paria, Moharreri, Fatemeh, Badiee, Amir Hossein, Hajivosugh, Negin, Rostami, Zohreh, Akhavanrezayat, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505986/
https://www.ncbi.nlm.nih.gov/pubmed/26199704
http://dx.doi.org/10.5812/ijp.25(3)2015.322
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author Behdani, Fatemeh
Badiee, Zahra
Hebrani, Paria
Moharreri, Fatemeh
Badiee, Amir Hossein
Hajivosugh, Negin
Rostami, Zohreh
Akhavanrezayat, Amir
author_facet Behdani, Fatemeh
Badiee, Zahra
Hebrani, Paria
Moharreri, Fatemeh
Badiee, Amir Hossein
Hajivosugh, Negin
Rostami, Zohreh
Akhavanrezayat, Amir
author_sort Behdani, Fatemeh
collection PubMed
description BACKGROUND: Thalassemia is an inherited blood disease. It is a serious public health problem throughout the Mediterranean region, the Middle East and the Indian subcontinent, as well as in Southeast Asia. OBJECTIVES: Thalassemia is an inherited blood disease. It is a serious public health problem. In this study we assessed psychological aspects in Iranian children and adolescents with thalassemia major. PATIENTS AND METHODS: In this case-control study sixty healthy subjects aged 7-18 years and Sixty Patients with confirmed diagnosis of major thalassemia were enrolled. After obtaining informed consent from parents of all participating thalassemia patients and healthycontrols, we assessed psychological aspects and quality of life by Pediatric Quality of LifeTM (PedsQL™), Strengths and Difficulties Questionnaires (SDQ), State and Trait Anxiety, Children's Depression Inventory (CDI). RESULTS: The results of this study indicate that there are significant changes in depression, anxiety, QOL and behavioral screening between children with thalassemia major compared with healthy subjects by means of both parents and children reports. According to the results, children with thalassemia major have more psychological problems than healthy ones. Patients with thalassemia have a lower QOL than their peers (P = 0.001), the rate of depression is higher in this group (P = 0.015), Also behavioral problems in these children are more than healthy subjects (P = 0.009). CONCLUSIONS: We recommend appropriate treatment and counseling procedures in addition to specific treatment of thalassemia. According to the results we suggest to establish pediatric psychiatric clinics beside thalassemic clinics to cure psychological aspects of the disease.
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spelling pubmed-45059862015-07-21 Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study Behdani, Fatemeh Badiee, Zahra Hebrani, Paria Moharreri, Fatemeh Badiee, Amir Hossein Hajivosugh, Negin Rostami, Zohreh Akhavanrezayat, Amir Iran J Pediatr Research Article BACKGROUND: Thalassemia is an inherited blood disease. It is a serious public health problem throughout the Mediterranean region, the Middle East and the Indian subcontinent, as well as in Southeast Asia. OBJECTIVES: Thalassemia is an inherited blood disease. It is a serious public health problem. In this study we assessed psychological aspects in Iranian children and adolescents with thalassemia major. PATIENTS AND METHODS: In this case-control study sixty healthy subjects aged 7-18 years and Sixty Patients with confirmed diagnosis of major thalassemia were enrolled. After obtaining informed consent from parents of all participating thalassemia patients and healthycontrols, we assessed psychological aspects and quality of life by Pediatric Quality of LifeTM (PedsQL™), Strengths and Difficulties Questionnaires (SDQ), State and Trait Anxiety, Children's Depression Inventory (CDI). RESULTS: The results of this study indicate that there are significant changes in depression, anxiety, QOL and behavioral screening between children with thalassemia major compared with healthy subjects by means of both parents and children reports. According to the results, children with thalassemia major have more psychological problems than healthy ones. Patients with thalassemia have a lower QOL than their peers (P = 0.001), the rate of depression is higher in this group (P = 0.015), Also behavioral problems in these children are more than healthy subjects (P = 0.009). CONCLUSIONS: We recommend appropriate treatment and counseling procedures in addition to specific treatment of thalassemia. According to the results we suggest to establish pediatric psychiatric clinics beside thalassemic clinics to cure psychological aspects of the disease. Kowsar 2015-06-27 2015-06 /pmc/articles/PMC4505986/ /pubmed/26199704 http://dx.doi.org/10.5812/ijp.25(3)2015.322 Text en Copyright © 2015, Growth & Development Research Center. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
spellingShingle Research Article
Behdani, Fatemeh
Badiee, Zahra
Hebrani, Paria
Moharreri, Fatemeh
Badiee, Amir Hossein
Hajivosugh, Negin
Rostami, Zohreh
Akhavanrezayat, Amir
Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study
title Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study
title_full Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study
title_fullStr Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study
title_full_unstemmed Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study
title_short Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study
title_sort psychological aspects in children and adolescents with major thalassemia: a case-control study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505986/
https://www.ncbi.nlm.nih.gov/pubmed/26199704
http://dx.doi.org/10.5812/ijp.25(3)2015.322
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