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Pharmacokinetic Profiles of Active Ingredients and Its Metabolites Derived from Rikkunshito, a Ghrelin Enhancer, in Healthy Japanese Volunteers: A Cross-Over, Randomized Study

BACKGROUND: Rikkunshito, a traditional Japanese (Kampo) medicine, has been used to treat upper gastrointestinal disorders such as functional dyspepsia and gastroesophageal reflux. This study investigated the exposure and pharmacokinetics of the ingredients of rikkunshito in healthy volunteers. METHO...

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Detalles Bibliográficos
Autores principales:	Kitagawa, Hiroyuki, Munekage, Masaya, Matsumoto, Takashi, Sadakane, Chiharu, Fukutake, Miwako, Aoki, Katsuyuki, Watanabe, Junko, Maemura, Kazuya, Hattori, Tomohisa, Kase, Yosio, Uezono, Yasuhito, Inui, Akio, Hanazaki, Kazuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506051/ https://www.ncbi.nlm.nih.gov/pubmed/26186592 http://dx.doi.org/10.1371/journal.pone.0133159

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