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Peloruside A is a microtubule-stabilizing agent with exceptional anti-migratory properties in human endothelial cells
Peloruside A is a novel antimitotic drug originally isolated from the marine sponge Mycale hentschieli. Previous studies showed that peloruside A stabilizes microtubules by binding to a site on tubulin distinct from paclitaxel, another microtubule stabilizing drug. Peloruside A blocks mitosis, but l...
Autores principales: | Ganguly, Anutosh, Cabral, Fernando, Yang, Hailing, Patel, Kamala D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506362/ https://www.ncbi.nlm.nih.gov/pubmed/26244166 |
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