Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target

INTRODUCTION: IGF2BP3 (IMP3) is a mRNA binding protein that regulates IGF2 translation and function during embryogenesis. Because IGF2BP3 is undetectable in adult human tissues except the testis, and increased IGF2BP3 expression has been noted in several cancers, it is considered a cancer testis (CT...

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Detalles Bibliográficos
Autores principales: Shantha Kumara, HMC, Kirchoff, Daniel, Caballero, Otavia L., Su, Tao, Ahmed, Aqeel, Herath, Sonali AC., Njoh, Linda, Cekic, Vesna, Simpson, Andrew J., Cordon-Cardo, Carlos, Whelan, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506364/
https://www.ncbi.nlm.nih.gov/pubmed/26244168

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