Cargando…
Red ginseng extract blocks histamine-dependent itch by inhibition of H1R/TRPV1 pathway in sensory neurons
BACKGROUND: Korean Red Ginseng—a steamed root of Panax ginseng Meyer—has long been used as a traditional medicine in Asian countries. Its antipruritic effect was recently found, but no molecular mechanisms were revealed. Thus, the current study focused on determining the underlying molecular mechani...
Autores principales: | Jang, Yongwoo, Lee, Wook-Joo, Hong, Gyu-Sang, Shim, Won-Sik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506365/ https://www.ncbi.nlm.nih.gov/pubmed/26199558 http://dx.doi.org/10.1016/j.jgr.2015.01.004 |
Ejemplares similares
-
Crotamiton, an Anti-Scabies Agent, Suppresses Histamine- and Chloroquine-Induced Itch Pathways in Sensory Neurons and Alleviates Scratching in Mice
por: Choi, Da-Som, et al.
Publicado: (2020) -
Pirt, a TRPV1 Modulator, Is Required for Histamine-Dependent and -Independent Itch
por: Patel, Kush N., et al.
Publicado: (2011) -
Osthole inhibits histamine-dependent itch via modulating TRPV1 activity
por: Yang, Niu-Niu, et al.
Publicado: (2016) -
TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch
por: Jian, Tunyu, et al.
Publicado: (2016) -
TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch
por: Wilzopolski, Jenny, et al.
Publicado: (2021)