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Overexpression of connexin 43 reduces melanoma proliferative and metastatic capacity
BACKGROUND: Alterations in connexin 43 (Cx43) expression and/or gap junction (GJ)-mediated intercellular communication are implicated in cancer pathogenesis. Herein, we have investigated the role of Cx43 in melanoma cell proliferation and apoptosis sensitivity in vitro, as well as metastatic capabil...
Autores principales: | Tittarelli, A, Guerrero, I, Tempio, F, Gleisner, M A, Avalos, I, Sabanegh, S, Ortíz, C, Michea, L, López, M N, Mendoza-Naranjo, A, Salazar-Onfray, F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506378/ https://www.ncbi.nlm.nih.gov/pubmed/26135897 http://dx.doi.org/10.1038/bjc.2015.162 |
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