Overexpression of connexin 43 reduces melanoma proliferative and metastatic capacity

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BACKGROUND: Alterations in connexin 43 (Cx43) expression and/or gap junction (GJ)-mediated intercellular communication are implicated in cancer pathogenesis. Herein, we have investigated the role of Cx43 in melanoma cell proliferation and apoptosis sensitivity in vitro, as well as metastatic capabil...

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Detalles Bibliográficos
Autores principales: Tittarelli, A, Guerrero, I, Tempio, F, Gleisner, M A, Avalos, I, Sabanegh, S, Ortíz, C, Michea, L, López, M N, Mendoza-Naranjo, A, Salazar-Onfray, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506378/
https://www.ncbi.nlm.nih.gov/pubmed/26135897
http://dx.doi.org/10.1038/bjc.2015.162
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