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Altering cancer transcriptomes using epigenomic inhibitors
BACKGROUND: Due to the hyper-activation of WNT signaling in a variety of cancer types, there has been a strong drive to develop pathway-specific inhibitors with the eventual goal of providing a chemotherapeutic antagonist of WNT signaling to cancer patients. A new category of drugs, called epigeneti...
Autores principales: | Gaddis, Malaina, Gerrard, Diana, Frietze, Seth, Farnham, Peggy J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506402/ https://www.ncbi.nlm.nih.gov/pubmed/26191083 http://dx.doi.org/10.1186/1756-8935-8-9 |
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