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Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer?

Patients with colorectal cancer admitted to the emergency room are generally at more advanced stage of the disease and are usually submitted to a resection with curative intent in a smaller scale. In such scenario, one of the aspects to be considered is whether the principles of oncologic resection...

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Autores principales: Teixeira, Frederico, Akaishi, Eduardo Hiroshi, Ushinohama, Adriano Zuardi, Dutra, Tiago Cypriano, Netto, Sérgio Dias do Couto, Utiyama, Edivaldo Massazo, Bernini, Celso Oliveira, Rasslan, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506407/
https://www.ncbi.nlm.nih.gov/pubmed/26191078
http://dx.doi.org/10.1186/1749-7922-10-5
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author Teixeira, Frederico
Akaishi, Eduardo Hiroshi
Ushinohama, Adriano Zuardi
Dutra, Tiago Cypriano
Netto, Sérgio Dias do Couto
Utiyama, Edivaldo Massazo
Bernini, Celso Oliveira
Rasslan, Samir
author_facet Teixeira, Frederico
Akaishi, Eduardo Hiroshi
Ushinohama, Adriano Zuardi
Dutra, Tiago Cypriano
Netto, Sérgio Dias do Couto
Utiyama, Edivaldo Massazo
Bernini, Celso Oliveira
Rasslan, Samir
author_sort Teixeira, Frederico
collection PubMed
description Patients with colorectal cancer admitted to the emergency room are generally at more advanced stage of the disease and are usually submitted to a resection with curative intent in a smaller scale. In such scenario, one of the aspects to be considered is whether the principles of oncologic resection are observed when those patients diagnosed with colon cancer are treated with surgery. We selected 87 patients with adenocarcinoma of colon and/or upper rectum submitted to an emergency surgical resection. The major variables reviewed retrospectively were: the extent of resection performed, the number of dissected regional lymph nodes and the overall survival rate. Intestinal obstruction was observed in 67 patients (77%) while perforation was found in 20 patients (23%). Seven (8%) specimens had circumferential compromised margins, all found in patients with T4 tumors combine with poor clinical status. The number of dissected regional lymph nodes was greater than, or equal to, 12 in 71% of patients. While the average days of stay in the ICU was 5.7 days, the median was 3 days. The morbidity and peri-operative mortality stood at 33.6% and 20%, respectively. The outcome of an emergency surgery of colorectal cancer observed in this study was similar to those found in the literature. The principles of oncologic resection were respected when considering and analyzing the extent of the resection, the surgical margins and the number of dissected lymph nodes.
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spelling pubmed-45064072015-07-19 Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer? Teixeira, Frederico Akaishi, Eduardo Hiroshi Ushinohama, Adriano Zuardi Dutra, Tiago Cypriano Netto, Sérgio Dias do Couto Utiyama, Edivaldo Massazo Bernini, Celso Oliveira Rasslan, Samir World J Emerg Surg Review Patients with colorectal cancer admitted to the emergency room are generally at more advanced stage of the disease and are usually submitted to a resection with curative intent in a smaller scale. In such scenario, one of the aspects to be considered is whether the principles of oncologic resection are observed when those patients diagnosed with colon cancer are treated with surgery. We selected 87 patients with adenocarcinoma of colon and/or upper rectum submitted to an emergency surgical resection. The major variables reviewed retrospectively were: the extent of resection performed, the number of dissected regional lymph nodes and the overall survival rate. Intestinal obstruction was observed in 67 patients (77%) while perforation was found in 20 patients (23%). Seven (8%) specimens had circumferential compromised margins, all found in patients with T4 tumors combine with poor clinical status. The number of dissected regional lymph nodes was greater than, or equal to, 12 in 71% of patients. While the average days of stay in the ICU was 5.7 days, the median was 3 days. The morbidity and peri-operative mortality stood at 33.6% and 20%, respectively. The outcome of an emergency surgery of colorectal cancer observed in this study was similar to those found in the literature. The principles of oncologic resection were respected when considering and analyzing the extent of the resection, the surgical margins and the number of dissected lymph nodes. BioMed Central 2015-02-14 /pmc/articles/PMC4506407/ /pubmed/26191078 http://dx.doi.org/10.1186/1749-7922-10-5 Text en © Teixeira et al.; licensee BioMed Central. 2015 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Teixeira, Frederico
Akaishi, Eduardo Hiroshi
Ushinohama, Adriano Zuardi
Dutra, Tiago Cypriano
Netto, Sérgio Dias do Couto
Utiyama, Edivaldo Massazo
Bernini, Celso Oliveira
Rasslan, Samir
Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer?
title Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer?
title_full Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer?
title_fullStr Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer?
title_full_unstemmed Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer?
title_short Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer?
title_sort can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506407/
https://www.ncbi.nlm.nih.gov/pubmed/26191078
http://dx.doi.org/10.1186/1749-7922-10-5
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