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Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells
BACKGROUND: The vasculature of the brain is composed of endothelial cells, pericytes and astrocytic processes. The endothelial cells are the critical interface between the blood and the CNS parenchyma and are a critical component of the blood-brain barrier (BBB). These cells are innately programmed...
Autores principales: | O’Carroll, Simon J., Kho, Dan Ting, Wiltshire, Rachael, Nelson, Vicky, Rotimi, Odunayo, Johnson, Rebecca, Angel, Catherine E., Graham, E. Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506411/ https://www.ncbi.nlm.nih.gov/pubmed/26152369 http://dx.doi.org/10.1186/s12974-015-0346-0 |
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