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Screening of potential target genes for cataract by analyzing mRNA expression profile of mouse Hsf4-null lens

BACKGROUND: Hsf4 is closely related to the development of cataract. However, the molecular mechanisms remain unknown. This study aimed to explore the molecular mechanisms that how Hsf4 mutations influence development of lens and thus lead to cataract in mouse. METHODS: The mRNA expression profile of...

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Detalles Bibliográficos
Autores principales: Zhao, Wenjuan, Zhao, Wenqing, Zhao, Jun, Wang, Dong, Li, Jinghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506420/
https://www.ncbi.nlm.nih.gov/pubmed/26187041
http://dx.doi.org/10.1186/s12886-015-0066-3

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