Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

BACKGROUND: Gene expression profiling is being widely applied in cancer research to identify biomarkers for clinical endpoint prediction. Since RNA-seq provides a powerful tool for transcriptome-based applications beyond the limitations of microarrays, we sought to systematically evaluate the perfor...

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Detalles Bibliográficos
Autores principales: Zhang, Wenqian, Yu, Ying, Hertwig, Falk, Thierry-Mieg, Jean, Zhang, Wenwei, Thierry-Mieg, Danielle, Wang, Jian, Furlanello, Cesare, Devanarayan, Viswanath, Cheng, Jie, Deng, Youping, Hero, Barbara, Hong, Huixiao, Jia, Meiwen, Li, Li, Lin, Simon M, Nikolsky, Yuri, Oberthuer, André, Qing, Tao, Su, Zhenqiang, Volland, Ruth, Wang, Charles, Wang, May D., Ai, Junmei, Albanese, Davide, Asgharzadeh, Shahab, Avigad, Smadar, Bao, Wenjun, Bessarabova, Marina, Brilliant, Murray H., Brors, Benedikt, Chierici, Marco, Chu, Tzu-Ming, Zhang, Jibin, Grundy, Richard G., He, Min Max, Hebbring, Scott, Kaufman, Howard L., Lababidi, Samir, Lancashire, Lee J., Li, Yan, Lu, Xin X., Luo, Heng, Ma, Xiwen, Ning, Baitang, Noguera, Rosa, Peifer, Martin, Phan, John H., Roels, Frederik, Rosswog, Carolina, Shao, Susan, Shen, Jie, Theissen, Jessica, Tonini, Gian Paolo, Vandesompele, Jo, Wu, Po-Yen, Xiao, Wenzhong, Xu, Joshua, Xu, Weihong, Xuan, Jiekun, Yang, Yong, Ye, Zhan, Dong, Zirui, Zhang, Ke K., Yin, Ye, Zhao, Chen, Zheng, Yuanting, Wolfinger, Russell D., Shi, Tieliu, Malkas, Linda H., Berthold, Frank, Wang, Jun, Tong, Weida, Shi, Leming, Peng, Zhiyu, Fischer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506430/
https://www.ncbi.nlm.nih.gov/pubmed/26109056
http://dx.doi.org/10.1186/s13059-015-0694-1

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