AAV2/8-humanFOXP3 gene therapy shows robust anti-atherosclerosis efficacy in LDLR-KO mice on high cholesterol diet

Inflammation is a key etiologic component in atherogenesis. Previously we demonstrated that adeno-associated virus (AAV) 2/8 gene delivery of Netrin1 inhibited atherosclerosis in the low density lipoprotein receptor knockout mice on high-cholesterol diet (LDLR-KO/HCD). One important finding from thi...

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Detalles Bibliográficos
Autores principales: Cao, M, Theus, S A, Straub, K D, Figueroa, J A, Mirandola, L, Chiriva-Internati, M, Hermonat, P L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506442/
https://www.ncbi.nlm.nih.gov/pubmed/26187646
http://dx.doi.org/10.1186/s12967-015-0597-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506442/
https://www.ncbi.nlm.nih.gov/pubmed/26187646
http://dx.doi.org/10.1186/s12967-015-0597-7

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