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AAV2/8-humanFOXP3 gene therapy shows robust anti-atherosclerosis efficacy in LDLR-KO mice on high cholesterol diet

Inflammation is a key etiologic component in atherogenesis. Previously we demonstrated that adeno-associated virus (AAV) 2/8 gene delivery of Netrin1 inhibited atherosclerosis in the low density lipoprotein receptor knockout mice on high-cholesterol diet (LDLR-KO/HCD). One important finding from thi...

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Detalles Bibliográficos
Autores principales:	Cao, M, Theus, S A, Straub, K D, Figueroa, J A, Mirandola, L, Chiriva-Internati, M, Hermonat, P L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506442/ https://www.ncbi.nlm.nih.gov/pubmed/26187646 http://dx.doi.org/10.1186/s12967-015-0597-7

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