Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activities

RNA helicases are implicated in most cellular RNA-dependent events. In eukaryotes however, only few have been functionally characterized. Upf1 is a RNA helicase essential for nonsense-mediated mRNA decay (NMD). Here, using magnetic tweezers and bulk assays, we observe that human Upf1 is able to tran...

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Detalles Bibliográficos
Autores principales: Fiorini, Francesca, Bagchi, Debjani, Le Hir, Hervé, Croquette, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506499/
https://www.ncbi.nlm.nih.gov/pubmed/26138914
http://dx.doi.org/10.1038/ncomms8581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506499/
https://www.ncbi.nlm.nih.gov/pubmed/26138914
http://dx.doi.org/10.1038/ncomms8581

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