NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis

NF-κB is constitutively activated in psoriatic epidermis. However, how activated NF-κB promotes keratinocyte hyperproliferation in psoriasis is largely unknown. Here we report that the NF-κB activation triggered by inflammatory cytokines induces the transcription of microRNA (miRNA) miR-31, one of t...

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Detalles Bibliográficos
Autores principales: Yan, Sha, Xu, Zhenyao, Lou, Fangzhou, Zhang, Lingyun, Ke, Fang, Bai, Jing, Liu, Zhaoyuan, Liu, Jinlin, Wang, Hong, Zhu, Huiyuan, Sun, Yang, Cai, Wei, Gao, Yuanyuan, Su, Bing, Li, Qun, Yang, Xiao, Yu, Jianxiu, Lai, Yuping, Yu, Xue-Zhong, Zheng, Yan, Shen, Nan, Chin, Y. Eugene, Wang, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506511/
https://www.ncbi.nlm.nih.gov/pubmed/26138368
http://dx.doi.org/10.1038/ncomms8652

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