Spontaneous CO Release from Ru(II)(CO)(2)–Protein Complexes in Aqueous Solution, Cells, and Mice**

We demonstrate that Ru(II)(CO)(2)–protein complexes, formed by the reaction of the hydrolytic decomposition products of [fac-RuCl(κ(2)-H(2)NCH(2)CO(2))(CO)(3)] (CORM-3) with histidine residues exposed on the surface of proteins, spontaneously release CO in aqueous solution, cells, and mice. CO relea...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaves-Ferreira, Miguel, Albuquerque, Inês S, Matak-Vinkovic, Dijana, Coelho, Ana C, Carvalho, Sandra M, Saraiva, Lígia M, Romão, Carlos C, Bernardes, Gonçalo J L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506567/
https://www.ncbi.nlm.nih.gov/pubmed/25477186
http://dx.doi.org/10.1002/anie.201409344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506567/
https://www.ncbi.nlm.nih.gov/pubmed/25477186
http://dx.doi.org/10.1002/anie.201409344

Ejemplares similares