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Targeting a Dynamic Protein–Protein Interaction: Fragment Screening against the Malaria Myosin A Motor Complex

Motility is a vital feature of the complex life cycle of Plasmodium falciparum, the apicomplexan parasite that causes human malaria. Processes such as host cell invasion are thought to be powered by a conserved actomyosin motor (containing myosin A or myoA), correct localization of which is dependen...

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Detalles Bibliográficos
Autores principales: Douse, Christopher H, Vrielink, Nina, Wenlin, Zhang, Cota, Ernesto, Tate, Edward W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506568/
https://www.ncbi.nlm.nih.gov/pubmed/25367834
http://dx.doi.org/10.1002/cmdc.201402357