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Targeting a Dynamic Protein–Protein Interaction: Fragment Screening against the Malaria Myosin A Motor Complex
Motility is a vital feature of the complex life cycle of Plasmodium falciparum, the apicomplexan parasite that causes human malaria. Processes such as host cell invasion are thought to be powered by a conserved actomyosin motor (containing myosin A or myoA), correct localization of which is dependen...
Autores principales: | Douse, Christopher H, Vrielink, Nina, Wenlin, Zhang, Cota, Ernesto, Tate, Edward W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506568/ https://www.ncbi.nlm.nih.gov/pubmed/25367834 http://dx.doi.org/10.1002/cmdc.201402357 |
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