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STAT3 polymorphism and Helicobacter pylori CagA strains with higher number of EPIYA-C segments independently increase the risk of gastric cancer

BACKGROUND: Because to date there is no available study on STAT3 polymorphism and gastric cancer in Western populations and taking into account that Helicobacter pylori CagA EPIYA-C segment deregulates SHP-2/ERK-JAK/STAT3 pathways, we evaluated whether the two variables are independently associated...

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Detalles Bibliográficos
Autores principales: Rocha, Gifone A, Rocha, Andreia MC, Gomes, Adriana D, Faria, César LL, Melo, Fabrício F, Batista, Sérgio A, Fernandes, Viviane C, Almeida, Nathálie BF, Teixeira, Kádima N, Brito, Kátia S, Queiroz, Dulciene Maria Magalhães
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506573/
https://www.ncbi.nlm.nih.gov/pubmed/26186918
http://dx.doi.org/10.1186/s12885-015-1533-1

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