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STAT3 polymorphism and Helicobacter pylori CagA strains with higher number of EPIYA-C segments independently increase the risk of gastric cancer
BACKGROUND: Because to date there is no available study on STAT3 polymorphism and gastric cancer in Western populations and taking into account that Helicobacter pylori CagA EPIYA-C segment deregulates SHP-2/ERK-JAK/STAT3 pathways, we evaluated whether the two variables are independently associated...
Autores principales: | Rocha, Gifone A, Rocha, Andreia MC, Gomes, Adriana D, Faria, César LL, Melo, Fabrício F, Batista, Sérgio A, Fernandes, Viviane C, Almeida, Nathálie BF, Teixeira, Kádima N, Brito, Kátia S, Queiroz, Dulciene Maria Magalhães |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506573/ https://www.ncbi.nlm.nih.gov/pubmed/26186918 http://dx.doi.org/10.1186/s12885-015-1533-1 |
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