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Detection of a TRAF1-ALK fusion in an anaplastic large cell lymphoma patient with chemotherapy and ALK inhibitor-resistant disease

BACKGROUND: The anaplastic lymphoma kinase (ALK) gene encodes a receptor tyrosine kinase, which was first identified as the fusion partner of the nucleophosmin (NPM1) gene in the recurrent t(2;5)(p23;q35) found in a subset of anaplastic large cell lymphoma (ALCL). Several distinct, non-NPM1, ALK fus...

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Detalles Bibliográficos
Autores principales:	Lawrence, Kasey, Berry, Brian, Handshoe, John, Hout, David, Mazzola, Rosetta, Morris, Stephan W, Saltman, David L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506579/ https://www.ncbi.nlm.nih.gov/pubmed/26187744 http://dx.doi.org/10.1186/s13104-015-1277-7

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