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Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum

BACKGROUND: Malaria invasion of red blood cells involves multiple parasite-specific targets that are easily accessible to inhibitory compounds, making it an attractive target for antimalarial development. However, no current antimalarial agents act against host cell invasion. RESULTS: Here, we demon...

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Detalles Bibliográficos
Autores principales: Wilson, Danny W, Goodman, Christopher D, Sleebs, Brad E, Weiss, Greta E, de Jong, Nienke WM, Angrisano, Fiona, Langer, Christine, Baum, Jake, Crabb, Brendan S, Gilson, Paul R, McFadden, Geoffrey I, Beeson, James G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506589/
https://www.ncbi.nlm.nih.gov/pubmed/26187647
http://dx.doi.org/10.1186/s12915-015-0162-0