Neurophysiological Correlates of Central Fatigue in Healthy Subjects and Multiple Sclerosis Patients before and after Treatment with Amantadine

In ten healthy subjects and in ten patients suffering from Multiple Sclerosis (MS), we investigated the cortical functional changes induced by a standard fatiguing repetitive tapping task. The Cortical Silent Period (CSP), an intracortical, mainly GABA(B)-mediated inhibitory phenomenon, was recorded...

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Detalles Bibliográficos
Autores principales: Santarnecchi, Emiliano, Rossi, Simone, Bartalini, Sabina, Cincotta, Massimo, Giovannelli, Fabio, Tatti, Elisa, Ulivelli, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506817/
https://www.ncbi.nlm.nih.gov/pubmed/26236509
http://dx.doi.org/10.1155/2015/616242

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