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Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

Protein oxidation is involved in regulatory physiological events as well as in damage to tissues and is thought to play a key role in the pathophysiology of diseases and in the aging process. Protein-bound carbonyls represent a marker of global protein oxidation, as they are generated by multiple di...

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Detalles Bibliográficos
Autores principales: Weber, Daniela, Davies, Michael J., Grune, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506980/
https://www.ncbi.nlm.nih.gov/pubmed/26141921
http://dx.doi.org/10.1016/j.redox.2015.06.005