Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion

Our understanding of the key phosphorylation-dependent signalling pathways in the human malaria parasite, Plasmodium falciparum, remains rudimentary. Here we address this issue for the essential cGMP-dependent protein kinase, PfPKG. By employing chemical and genetic tools in combination with quantit...

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Detalles Bibliográficos
Autores principales: Alam, Mahmood M., Solyakov, Lev, Bottrill, Andrew R., Flueck, Christian, Siddiqui, Faiza A., Singh, Shailja, Mistry, Sharad, Viskaduraki, Maria, Lee, Kate, Hopp, Christine S., Chitnis, Chetan E., Doerig, Christian, Moon, Robert W., Green, Judith L., Holder, Anthony A., Baker, David A., Tobin, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507021/
https://www.ncbi.nlm.nih.gov/pubmed/26149123
http://dx.doi.org/10.1038/ncomms8285

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