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Economical analysis of saturation mutagenesis experiments

Saturation mutagenesis is a powerful technique for engineering proteins, metabolic pathways and genomes. In spite of its numerous applications, creating high-quality saturation mutagenesis libraries remains a challenge, as various experimental parameters influence in a complex manner the resulting d...

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Detalles Bibliográficos
Autores principales: Acevedo-Rocha, Carlos G., Reetz, Manfred T., Nov, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507136/
https://www.ncbi.nlm.nih.gov/pubmed/26190439
http://dx.doi.org/10.1038/srep10654