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Myeloid derived suppressor and dendritic cell subsets are related to clinical outcome in prostate cancer patients treated with prostate GVAX and ipilimumab
BACKGROUND: Cancer-related disturbances in myeloid lineage development, marked by high levels of myeloid-derived suppressor cells (MDSC) and impaired dendritic cell (DC) development, are associated with poor clinical outcome due to immune escape and therapy resistance. Redressing this balance may th...
Autores principales: | Santegoets, Saskia JAM, Stam, Anita GM, Lougheed, Sinéad M, Gall, Helen, Jooss, Karin, Sacks, Natalie, Hege, Kristen, Lowy, Israel, Scheper, Rik J, Gerritsen, Winald R, van den Eertwegh, Alfons JM, de Gruijl, Tanja D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507359/ https://www.ncbi.nlm.nih.gov/pubmed/26196012 http://dx.doi.org/10.1186/s40425-014-0031-3 |
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