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Mutations in presenilin 2 and its implications in Alzheimer’s disease and other dementia-associated disorders
Alzheimer’s disease (AD) is the most common form of dementia. Mutations in the genes encoding presenilin 1 (PSEN1), presenilin 2 (PSEN2), and amyloid precursor protein have been identified as the main genetic causes of familial AD. To date, more than 200 mutations have been described worldwide in PS...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507455/ https://www.ncbi.nlm.nih.gov/pubmed/26203236 http://dx.doi.org/10.2147/CIA.S85808 |