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Synergistic antitumor effect of adenovirus armed with Drosophila melanogaster deoxyribonucleoside kinase and nucleoside analogs for human breast carcinoma in vitro and in vivo

BACKGROUND: Suicide gene therapy in cancer can selectively kill tumors without damaging normal tissues. Drosophila melanogaster multisubstrate deoxyribonucleoside kinase (Dm-dNK), an original suicide kinase, makes use of the carcinomatous suicide gene therapy for broader substrate specificity and a...

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Detalles Bibliográficos
Autores principales:	Tang, Miao, Zu, Cong, He, Anning, Wang, Wenqian, Chen, Bo, Zheng, Xinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507493/ https://www.ncbi.nlm.nih.gov/pubmed/26203222 http://dx.doi.org/10.2147/DDDT.S81717

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