Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159

In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans.

Detalles Bibliográficos
Autores principales: Park, Soon-Nang, Ahn, Sug-Joon, Kook, Joong-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Microbiologia 2015
Materias:
Microbial Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507558/
https://www.ncbi.nlm.nih.gov/pubmed/26273281
http://dx.doi.org/10.1590/S1517-838246246220130209
Descripción
Sumario:In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans.

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