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Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159

In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans.

Detalles Bibliográficos
Autores principales: Park, Soon-Nang, Ahn, Sug-Joon, Kook, Joong-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Microbiologia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507558/
https://www.ncbi.nlm.nih.gov/pubmed/26273281
http://dx.doi.org/10.1590/S1517-838246246220130209
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author Park, Soon-Nang
Ahn, Sug-Joon
Kook, Joong-Ki
author_facet Park, Soon-Nang
Ahn, Sug-Joon
Kook, Joong-Ki
author_sort Park, Soon-Nang
collection PubMed
description In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans.
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spelling pubmed-45075582015-08-13 Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159 Park, Soon-Nang Ahn, Sug-Joon Kook, Joong-Ki Braz J Microbiol Microbial Physiology In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans. Sociedade Brasileira de Microbiologia 2015-06-01 /pmc/articles/PMC4507558/ /pubmed/26273281 http://dx.doi.org/10.1590/S1517-838246246220130209 Text en Copyright © 2015, Sociedade Brasileira de Microbiologia http://creativecommons.org/licenses/by/3.0/ All the content of the journal, except where otherwise noted, is licensed under a Creative Commons License CC BY-NC.
spellingShingle Microbial Physiology
Park, Soon-Nang
Ahn, Sug-Joon
Kook, Joong-Ki
Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159
title Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159
title_full Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159
title_fullStr Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159
title_full_unstemmed Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159
title_short Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159
title_sort oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in streptococcus mutans ua159
topic Microbial Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507558/
https://www.ncbi.nlm.nih.gov/pubmed/26273281
http://dx.doi.org/10.1590/S1517-838246246220130209
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