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Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159
In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans.
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Microbiologia
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507558/ https://www.ncbi.nlm.nih.gov/pubmed/26273281 http://dx.doi.org/10.1590/S1517-838246246220130209 |
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author | Park, Soon-Nang Ahn, Sug-Joon Kook, Joong-Ki |
author_facet | Park, Soon-Nang Ahn, Sug-Joon Kook, Joong-Ki |
author_sort | Park, Soon-Nang |
collection | PubMed |
description | In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans. |
format | Online Article Text |
id | pubmed-4507558 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Sociedade Brasileira de Microbiologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-45075582015-08-13 Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159 Park, Soon-Nang Ahn, Sug-Joon Kook, Joong-Ki Braz J Microbiol Microbial Physiology In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans. Sociedade Brasileira de Microbiologia 2015-06-01 /pmc/articles/PMC4507558/ /pubmed/26273281 http://dx.doi.org/10.1590/S1517-838246246220130209 Text en Copyright © 2015, Sociedade Brasileira de Microbiologia http://creativecommons.org/licenses/by/3.0/ All the content of the journal, except where otherwise noted, is licensed under a Creative Commons License CC BY-NC. |
spellingShingle | Microbial Physiology Park, Soon-Nang Ahn, Sug-Joon Kook, Joong-Ki Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159 |
title | Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in
Streptococcus mutans UA159 |
title_full | Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in
Streptococcus mutans UA159 |
title_fullStr | Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in
Streptococcus mutans UA159 |
title_full_unstemmed | Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in
Streptococcus mutans UA159 |
title_short | Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in
Streptococcus mutans UA159 |
title_sort | oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in
streptococcus mutans ua159 |
topic | Microbial Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507558/ https://www.ncbi.nlm.nih.gov/pubmed/26273281 http://dx.doi.org/10.1590/S1517-838246246220130209 |
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