Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in plasma and bioequivalent buffers: Applications to absorption, brain distribution, and pharmacokinetic studies

The purpose of this study is to develop and validate an UPLC-MS/MS method to quantify ethoxzolamide in plasma (EZ) and apply the method to absorption, brain distribution, as well as pharmacokinetic studies. A C(18) column was used with 0.1% of formic acid in acetonitrile and 0.1% of formic acid in w...

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Detalles Bibliográficos
Autores principales: Gao, Song, Zhao, Jing, Yin, Taijun, Ma, Yong, Xu, Beibei, Moore, Anthony N., Dash, Pramod K., Hu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507571/
https://www.ncbi.nlm.nih.gov/pubmed/25706567
http://dx.doi.org/10.1016/j.jchromb.2015.01.034

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