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Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles

In this study, we developed a reflective localized surface plasmon resonance (LSPR) optical fiber sensor, based on silver nanoparticles (Ag NPs). To enhance the sensitivity of the LSPR optical sensor, two key parameters were optimized, the length of the sensing area and the coating time of the Ag NP...

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Detalles Bibliográficos
Autores principales: Chen, Jiangping, Shi, Se, Su, Rongxin, Qi, Wei, Huang, Renliang, Wang, Mengfan, Wang, Libing, He, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507690/
https://www.ncbi.nlm.nih.gov/pubmed/26016910
http://dx.doi.org/10.3390/s150612205
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author Chen, Jiangping
Shi, Se
Su, Rongxin
Qi, Wei
Huang, Renliang
Wang, Mengfan
Wang, Libing
He, Zhimin
author_facet Chen, Jiangping
Shi, Se
Su, Rongxin
Qi, Wei
Huang, Renliang
Wang, Mengfan
Wang, Libing
He, Zhimin
author_sort Chen, Jiangping
collection PubMed
description In this study, we developed a reflective localized surface plasmon resonance (LSPR) optical fiber sensor, based on silver nanoparticles (Ag NPs). To enhance the sensitivity of the LSPR optical sensor, two key parameters were optimized, the length of the sensing area and the coating time of the Ag NPs. A sensing length of 1.5 cm and a 1-h coating time proved to be suitable conditions to produce highly sensitive sensors for biosensing. The optimized sensor has a high refractive index sensitivity of 387 nm/RIU, which is much higher than that of other reported individual silver nanoparticles in solutions. Moreover, the sensor was further modified with antigen to act as a biosensor. Distinctive wavelength shifts were found after each surface modification step. In addition, the reflective LSPR optical fiber sensor has high reproducibility and stability.
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spelling pubmed-45076902015-07-22 Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles Chen, Jiangping Shi, Se Su, Rongxin Qi, Wei Huang, Renliang Wang, Mengfan Wang, Libing He, Zhimin Sensors (Basel) Article In this study, we developed a reflective localized surface plasmon resonance (LSPR) optical fiber sensor, based on silver nanoparticles (Ag NPs). To enhance the sensitivity of the LSPR optical sensor, two key parameters were optimized, the length of the sensing area and the coating time of the Ag NPs. A sensing length of 1.5 cm and a 1-h coating time proved to be suitable conditions to produce highly sensitive sensors for biosensing. The optimized sensor has a high refractive index sensitivity of 387 nm/RIU, which is much higher than that of other reported individual silver nanoparticles in solutions. Moreover, the sensor was further modified with antigen to act as a biosensor. Distinctive wavelength shifts were found after each surface modification step. In addition, the reflective LSPR optical fiber sensor has high reproducibility and stability. MDPI 2015-05-26 /pmc/articles/PMC4507690/ /pubmed/26016910 http://dx.doi.org/10.3390/s150612205 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chen, Jiangping
Shi, Se
Su, Rongxin
Qi, Wei
Huang, Renliang
Wang, Mengfan
Wang, Libing
He, Zhimin
Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles
title Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles
title_full Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles
title_fullStr Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles
title_full_unstemmed Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles
title_short Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles
title_sort optimization and application of reflective lspr optical fiber biosensors based on silver nanoparticles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507690/
https://www.ncbi.nlm.nih.gov/pubmed/26016910
http://dx.doi.org/10.3390/s150612205
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