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Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles
In this study, we developed a reflective localized surface plasmon resonance (LSPR) optical fiber sensor, based on silver nanoparticles (Ag NPs). To enhance the sensitivity of the LSPR optical sensor, two key parameters were optimized, the length of the sensing area and the coating time of the Ag NP...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507690/ https://www.ncbi.nlm.nih.gov/pubmed/26016910 http://dx.doi.org/10.3390/s150612205 |
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author | Chen, Jiangping Shi, Se Su, Rongxin Qi, Wei Huang, Renliang Wang, Mengfan Wang, Libing He, Zhimin |
author_facet | Chen, Jiangping Shi, Se Su, Rongxin Qi, Wei Huang, Renliang Wang, Mengfan Wang, Libing He, Zhimin |
author_sort | Chen, Jiangping |
collection | PubMed |
description | In this study, we developed a reflective localized surface plasmon resonance (LSPR) optical fiber sensor, based on silver nanoparticles (Ag NPs). To enhance the sensitivity of the LSPR optical sensor, two key parameters were optimized, the length of the sensing area and the coating time of the Ag NPs. A sensing length of 1.5 cm and a 1-h coating time proved to be suitable conditions to produce highly sensitive sensors for biosensing. The optimized sensor has a high refractive index sensitivity of 387 nm/RIU, which is much higher than that of other reported individual silver nanoparticles in solutions. Moreover, the sensor was further modified with antigen to act as a biosensor. Distinctive wavelength shifts were found after each surface modification step. In addition, the reflective LSPR optical fiber sensor has high reproducibility and stability. |
format | Online Article Text |
id | pubmed-4507690 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-45076902015-07-22 Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles Chen, Jiangping Shi, Se Su, Rongxin Qi, Wei Huang, Renliang Wang, Mengfan Wang, Libing He, Zhimin Sensors (Basel) Article In this study, we developed a reflective localized surface plasmon resonance (LSPR) optical fiber sensor, based on silver nanoparticles (Ag NPs). To enhance the sensitivity of the LSPR optical sensor, two key parameters were optimized, the length of the sensing area and the coating time of the Ag NPs. A sensing length of 1.5 cm and a 1-h coating time proved to be suitable conditions to produce highly sensitive sensors for biosensing. The optimized sensor has a high refractive index sensitivity of 387 nm/RIU, which is much higher than that of other reported individual silver nanoparticles in solutions. Moreover, the sensor was further modified with antigen to act as a biosensor. Distinctive wavelength shifts were found after each surface modification step. In addition, the reflective LSPR optical fiber sensor has high reproducibility and stability. MDPI 2015-05-26 /pmc/articles/PMC4507690/ /pubmed/26016910 http://dx.doi.org/10.3390/s150612205 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chen, Jiangping Shi, Se Su, Rongxin Qi, Wei Huang, Renliang Wang, Mengfan Wang, Libing He, Zhimin Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles |
title | Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles |
title_full | Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles |
title_fullStr | Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles |
title_full_unstemmed | Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles |
title_short | Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles |
title_sort | optimization and application of reflective lspr optical fiber biosensors based on silver nanoparticles |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507690/ https://www.ncbi.nlm.nih.gov/pubmed/26016910 http://dx.doi.org/10.3390/s150612205 |
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