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Transdifferentiation mediated tumor suppression by the endoplasmic reticulum stress sensor IRE-1 in C. elegans

Deciphering effective ways to suppress tumor progression and to overcome acquired apoptosis resistance of tumor cells are major challenges in the tumor therapy field. We propose a new concept by which tumor progression can be suppressed by manipulating tumor cell identity. In this study, we examined...

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Detalles Bibliográficos
Autores principales: Levi-Ferber, Mor, Gian, Hai, Dudkevich, Reut, Henis-Korenblit, Sivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507713/
https://www.ncbi.nlm.nih.gov/pubmed/26192965
http://dx.doi.org/10.7554/eLife.08005