Conformational Stability and Pathogenic Misfolding of the Integral Membrane Protein PMP22

[Image: see text] Despite broad biochemical relevance, our understanding of the physiochemical reactions that limit the assembly and cellular trafficking of integral membrane proteins remains superficial. In this work, we report the first experimental assessment of the relationship between the confo...

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Detalles Bibliográficos
Autores principales: Schlebach, Jonathan P., Narayan, Malathi, Alford, Catherine, Mittendorf, Kathleen F., Carter, Bruce D., Li, Jun, Sanders, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507940/
https://www.ncbi.nlm.nih.gov/pubmed/26102530
http://dx.doi.org/10.1021/jacs.5b03743

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