L-Aminoacid Oxidase from Bothrops leucurus Venom Induces Nephrotoxicity via Apoptosis and Necrosis

Acute renal failure is a common complication caused by Bothrops viper envenomation. In this study, the nefrotoxicity of a main component of B. leucurus venom called L-aminoacid oxidase (LAAO-Bl) was evaluated by using tubular epithelial cell lines MDCK and HK-2 and perfused kidney from rats. LAAO-Bl...

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Detalles Bibliográficos
Autores principales: Morais, Isabel C. O., Pereira, Gustavo J. S., Orzáez, M., Jorge, Roberta J. B., Bincoletto, Claudia, Toyama, Marcos H., Monteiro, Helena S. A., Smaili, Soraya S., Pérez-Payá, Enrique, Martins, Alice M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508040/
https://www.ncbi.nlm.nih.gov/pubmed/26193352
http://dx.doi.org/10.1371/journal.pone.0132569

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