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Magnetic resonance-guided regional gene delivery strategy using a tumor stroma-permeable nanocarrier for pancreatic cancer

BACKGROUND: Gene therapy is a very promising technology for treatment of pancreatic ductal adenocarcinoma (PDAC). However, its application has been limited by the abundant stromal response in the tumor microenvironment. The aim of this study was to prepare a dendrimer-based gene-free loading vector...

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Detalles Bibliográficos
Autores principales: Wang, Qingbing, Li, Jianfeng, An, Sai, Chen, Yi, Jiang, Chen, Wang, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508066/
https://www.ncbi.nlm.nih.gov/pubmed/26203245
http://dx.doi.org/10.2147/IJN.S84930