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Lipidoid Nanoparticles for siRNA Delivery to the Intestinal Epithelium: In Vitro Investigations in a Caco-2 Model

Short interfering ribonucleic acid (siRNA) therapeutics show promise for the treatment of intestinal diseases by specifically suppressing the expression of disease relevant proteins. Recently, a class of lipid-like materials termed “lipidoids” have been shown to potently deliver siRNA to the liver a...

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Detalles Bibliográficos
Autores principales:	Ball, Rebecca L., Knapp, Christopher M., Whitehead, Kathryn A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508104/ https://www.ncbi.nlm.nih.gov/pubmed/26192592 http://dx.doi.org/10.1371/journal.pone.0133154

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