Cargando…

Protective role of 5-azacytidine on myocardial infarction is associated with modulation of macrophage phenotype and inhibition of fibrosis

We examined whether a shift in macrophage phenotype could be therapeutic for myocardial infarction (MI). The mouse macrophage cell line RAW264.7 was stimulated with peptidoglycan (PGN), with or without 5-azacytidine (5AZ) treatment. MI was induced by ligation of the left anterior descending coronary...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Yong Sook, Kang, Wan Seok, Kwon, Jin Sook, Hong, Moon Hwa, Jeong, Hye-yun, Jeong, Hae Chang, Jeong, Myung Ho, Ahn, Youngkeun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508142/ https://www.ncbi.nlm.nih.gov/pubmed/24571348 http://dx.doi.org/10.1111/jcmm.12248

Ejemplares similares

5-Azacytidine modulates interferon regulatory factor 1 in macrophages to exert a cardioprotective effect
por: Jeong, Hye-yun, et al.
Publicado: (2015)

Intramyocardial Injection of Stem Cells in Pig Myocardial Infarction Model: The First Trial in Korea
por: Kim, Min Chul, et al.
Publicado: (2017)

Restoration of angiogenic capacity of diabetes-insulted mesenchymal stem cells by oxytocin
por: Kim, Yong Sook, et al.
Publicado: (2013)

False Positive ST-Segment Elevation Myocardial Infarction
por: Jeong, Hae Chang, et al.
Publicado: (2013)

Role of Intravascular Ultrasound in Patients with Acute Myocardial Infarction
por: Hong, Young Joon, et al.
Publicado: (2015)

Impact of Smoking on Clinical Outcomes in Female Patients with Acute Myocardial Infarction
por: Jeong, Yun Ah, et al.
Publicado: (2015)

Genistein Promotes Endothelial Colony-Forming Cell (ECFC) Bioactivities and Cardiac Regeneration in Myocardial Infarction
por: Lee, Sang Hun, et al.
Publicado: (2014)

The optimization of cell therapy by combinational application with apicidin-treated mesenchymal stem cells after myocardial infarction
por: Cho, Dong Im, et al.
Publicado: (2017)

Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages
por: Cho, Dong-Im, et al.
Publicado: (2014)

Predictors of Recovery of Left Ventricular Systolic Dysfunction after Acute Myocardial Infarction: From the Korean Acute Myocardial Infarction Registry and Korean Myocardial Infarction Registry
por: Oh, Pyung Chun, et al.
Publicado: (2013)

Predictors of In-Hospital Mortality in Korean Patients with Acute Myocardial Infarction
por: Yang, Hae Young, et al.
Publicado: (2019)

New Horizons of Acute Myocardial Infarction: From the Korea Acute Myocardial Infarction Registry
por: Lee, Ki Hong, et al.
Publicado: (2013)

First Case Report of Simultaneously Detected Celiac and Cerebral Artery Aneurysms in a Patient with Myocardial Infarction
por: Oh, Seok, et al.
Publicado: (2021)

Current status of acute myocardial infarction in Korea
por: Kim, Yongcheol, et al.
Publicado: (2019)

A case of myocardial involvement in lung cancer that mimics ST segment elevation in myocardial infarction
por: Kim, Kye Hun, et al.
Publicado: (2014)

Angiopoietin-Like 4 Is Involved in the Poor Angiogenic Potential of High Glucose-Insulted Bone Marrow Stem Cells
por: Kim, Yong Sook, et al.
Publicado: (2014)

Effects of Fimasartan/Amlodipine Fixed-Dose Combination on Left Ventricular Systolic Function and Infarct Size in Rat Myocardial Infarction Model
por: Kim, Han Byul, et al.
Publicado: (2019)

Case report: A fatal case of myocardial infarction due to myocardial bridge and concomitant vasospasm: the role of stress gated SPECT
por: Oh, Seok, et al.
Publicado: (2023)

Outcomes of Nonagenarians with Acute Myocardial Infarction with or without Coronary Intervention
por: Oh, Seok, et al.
Publicado: (2022)

Differential Clinical Implications of High-Degree Atrioventricular Block Complicating ST-Segment Elevation Myocardial Infarction according to the Location of Infarction in the Era of Primary Percutaneous Coronary Intervention
por: Kim, Kyung Hwan, et al.
Publicado: (2016)

Our Dedicated Effort to Save a COVID-19 Confirmed Patient with Myocardial Infarction
por: Oh, Seok, et al.
Publicado: (2022)

Religious Affiliations and Clinical Outcomes in Korean Patients With Acute Myocardial Infarction
por: Oh, Seok, et al.
Publicado: (2022)

Posterior myocardial infarction caused by superdominant circumflex occlusion over an absent right coronary artery: Case report and review of literature
por: Oh, Seok, et al.
Publicado: (2021)

Percutaneous Coronary Intervention for Acute Myocardial Infarction in Elderly Patients with Renal Dysfunction: Results from the Korea Acute Myocardial Infarction Registry
por: Lim, Sang Yup, et al.
Publicado: (2013)

Association between baseline smoking status and clinical outcomes following myocardial infarction
por: Oh, Seok, et al.
Publicado: (2022)

Effects of Ivabradine on Left Ventricular Systolic Function and Cardiac Fibrosis in Rat Myocardial Ischemia-Reperfusion Model
por: Kim, Han Byul, et al.
Publicado: (2018)

Two Cases of Single Coronary Artery Ostium Presenting with Acute Myocardial Infarction: Right Coronary Artery Arising from Left Anterior Descending Artery
por: Kim, Min Chul, et al.
Publicado: (2021)

Timing of heart failure development and clinical outcomes in patients with acute myocardial infarction
por: Kim, Hyung Yoon, et al.
Publicado: (2023)

Long-term use of clopidogrel versus ticagrelor or prasugrel in patients with acute myocardial infarction after percutaneous coronary intervention
por: Kim, Yuri, et al.
Publicado: (2023)

A score for decision making during percutaneous coronary intervention in acute myocardial infarction patients with multivessel disease
por: Jeong, Hae Chang, et al.
Publicado: (2019)

2020 Korean Society of Myocardial Infarction Expert Consensus Document on Pharmacotherapy for Acute Myocardial Infarction
por: Kim, Hyun Kuk, et al.
Publicado: (2020)

Clinical Outcomes according to the Achievement of Target Low Density Lipoprotein-Cholesterol in Patients with Acute Myocardial Infarction
por: Ahn, Taehoon, et al.
Publicado: (2017)

Natural product derivative BIO promotes recovery after myocardial infarction via unique modulation of the cardiac microenvironment
por: Kim, Yong Sook, et al.
Publicado: (2016)

2021 Korean Society of Myocardial Infarction Expert Consensus Document on Revascularization for Acute Myocardial Infarction
por: Chang, Kiyuk, et al.
Publicado: (2021)

Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV
por: Oh, Seok, et al.
Publicado: (2022)

miR-18a-5p MicroRNA Increases Vascular Smooth Muscle Cell Differentiation by Downregulating Syndecan4
por: Kee, Hae Jin, et al.
Publicado: (2014)

Percutaneous Coronary Intervention for Double Ostial Lesion Presenting with ST-Segment Elevation Myocardial Infarction: Chronic Total Occlusion at Left Main Ostium and Plaque Rupture at Right Coronary Artery Ostium
por: Kim, Min Chul, et al.
Publicado: (2021)

Clinical impact of pulmonary hypertension on the outcomes of acute myocardial infarction patients with or without chronic obstructive pulmonary disease
por: Oh, Seok, et al.
Publicado: (2022)

Intervention of a Large Diagonal Branch for Acute Myocardial Infarction in a Patient with a New Variant of the Dual Left Anterior Descending Artery
por: Cho, Kyung Hoon, et al.
Publicado: (2022)

Functional Relevance of Macrophage-mediated Inflammation to Cardiac Regeneration
por: Kim, Yong Sook, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_kor1dp3ls4rqak63bs0s0b4ogn