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The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity
Lipid metabolism and receptor-mediated signaling are highly intertwined processes that cooperate to fulfill cellular functions and safeguard cellular homeostasis. Activation of Toll-like receptors (TLRs) leads to a complex cellular response, orchestrating a diverse range of inflammatory events that...
Autores principales: | Heinz, Leonhard X., Baumann, Christoph L., Köberlin, Marielle S., Snijder, Berend, Gawish, Riem, Shui, Guanghou, Sharif, Omar, Aspalter, Irene M., Müller, André C., Kandasamy, Richard K., Breitwieser, Florian P., Pichlmair, Andreas, Bruckner, Manuela, Rebsamen, Manuele, Blüml, Stephan, Karonitsch, Thomas, Fauster, Astrid, Colinge, Jacques, Bennett, Keiryn L., Knapp, Sylvia, Wenk, Markus R., Superti-Furga, Giulio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508342/ https://www.ncbi.nlm.nih.gov/pubmed/26095358 http://dx.doi.org/10.1016/j.celrep.2015.05.006 |
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