Pathophysiological Relationship between Infections and Systemic Vasculitis

The development of autoimmune disorders requires a combination of genetic, immunological, and environmental factors. Infectious agents, such as viruses and bacteria, can trigger autoimmunity through different mechanisms, and for systemic vasculitis in particular, microbial agents have been suggested...

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Detalles Bibliográficos
Autores principales: Muñoz-Grajales, Carolina, Pineda, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508375/
https://www.ncbi.nlm.nih.gov/pubmed/26236499
http://dx.doi.org/10.1155/2015/286783
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author Muñoz-Grajales, Carolina
Pineda, Juan C.
author_facet Muñoz-Grajales, Carolina
Pineda, Juan C.
author_sort Muñoz-Grajales, Carolina
collection PubMed
description The development of autoimmune disorders requires a combination of genetic, immunological, and environmental factors. Infectious agents, such as viruses and bacteria, can trigger autoimmunity through different mechanisms, and for systemic vasculitis in particular, microbial agents have been suggested to be involved in its pathogenesis. Although the exact mechanisms have not been fully elucidated, different theories have been postulated. This review considers the role of infections in the etiology of primary vasculitis, emphasizing their related immunological events.
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spelling pubmed-45083752015-08-02 Pathophysiological Relationship between Infections and Systemic Vasculitis Muñoz-Grajales, Carolina Pineda, Juan C. Autoimmune Dis Review Article The development of autoimmune disorders requires a combination of genetic, immunological, and environmental factors. Infectious agents, such as viruses and bacteria, can trigger autoimmunity through different mechanisms, and for systemic vasculitis in particular, microbial agents have been suggested to be involved in its pathogenesis. Although the exact mechanisms have not been fully elucidated, different theories have been postulated. This review considers the role of infections in the etiology of primary vasculitis, emphasizing their related immunological events. Hindawi Publishing Corporation 2015 2015-07-07 /pmc/articles/PMC4508375/ /pubmed/26236499 http://dx.doi.org/10.1155/2015/286783 Text en Copyright © 2015 C. Muñoz-Grajales and J. C. Pineda. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Muñoz-Grajales, Carolina
Pineda, Juan C.
Pathophysiological Relationship between Infections and Systemic Vasculitis
title Pathophysiological Relationship between Infections and Systemic Vasculitis
title_full Pathophysiological Relationship between Infections and Systemic Vasculitis
title_fullStr Pathophysiological Relationship between Infections and Systemic Vasculitis
title_full_unstemmed Pathophysiological Relationship between Infections and Systemic Vasculitis
title_short Pathophysiological Relationship between Infections and Systemic Vasculitis
title_sort pathophysiological relationship between infections and systemic vasculitis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508375/
https://www.ncbi.nlm.nih.gov/pubmed/26236499
http://dx.doi.org/10.1155/2015/286783
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