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A Genome-Wide CRISPR Library for High-Throughput Genetic Screening in Drosophila Cells
The simplicity of the CRISPR/Cas9 system of genome engineering has opened up the possibility of performing genome-wide targeted mutagenesis in cell lines, enabling screening for cellular phenotypes resulting from genetic aberrations. Drosophila cells have proven to be highly effective in identifying...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Science press ;, Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508376/ https://www.ncbi.nlm.nih.gov/pubmed/26165496 http://dx.doi.org/10.1016/j.jgg.2015.03.011 |